Spectroscopy has become an important tool in chemical analysis to identify unknown molecules. This course will serve as an introduction to UV, IR, NMR and MS-spectroscopy and their applications in industry and academic work. It is aimed at chemists and engineers who need a practical understanding of spectroscopy. Numerous example applications will be described including basic knowledge of instruments, instrument operation and spectrum identification. The course also covers instrument and spectrum troubleshooting. The course material is a combination of presentations, documents, software training and instrumental demonstrations as well as case studies.
Upon successful completion of this course, the delegates will be able to:
- To familiarize participants with the tools and techniques used in spectroscopy analysis and qualitative and quantitative methods
- To provide the skills, knowledge and understanding of principles and practices of spectroscopy analysis
- To understand the recent molecule identification methods.
- To provide all the necessary tools for users to expand their knowledge of analysis using spectroscopy technology
- To solve instrumental and molecular identifying problems
Molecular properties, the structure and bonding nature of organic compounds
Ultraviolet Spectroscopy:
- The natural of electronic excitations
- Principles of absorption spectroscopy
- Ultraviolet spectrum
- Solvent effect
- Effect of conformation and geometry
- Fieser-Kuhn rules for polyenes
Infrared Spectroscopy (IR):
- Mode of vibration and bending
- Bond properties and absorption trends
- IR spectrometer
- Reading of the spectra
- A survey of the important functional groups with examples
- Nuclear magnetic resonance spectroscopy:
- Nuclear spin states and magnetic moments
- Mechanism of energy absorption (resonance)
- The chemical shift and shielding
- Chemical equivalence integrals
- NMR spectrometer
- The 1H and 13C NMR spectra of important molecules
- Two-dimensional NMR spectra
Mass Spectroscopy (MS):
- Molecular formulas from isotope ratio data
- Some fragmentation patterns
- The mass spectrum
- Mass spectrometer
- Spectrum of many examples
- Problems and troubleshooting
- Exercises and discussion
- More details of the course outline can be provided on request
This course is intended for all Laboratory Chemists, Laboratory Technicians, Chemical Engineers, Instrument Engineers, Laboratory Supervisors, R&D and all laboratory technical staff.